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Opioid overdose

Medically reviewed by Asia, RN, BSN

Written by Justin Alcalde, AHA and American Red Cross instructor, CPR West Covina

Price and class details checked .

An opioid overdose can slow or stop a person's breathing. If someone cannot be woken or is not breathing normally, call 911, give naloxone if you have it, and stay with them. Each guide below answers one question, from what to do in the first minutes to what California law covers, and every page lists the sources it relies on.

Learn these steps before you ever face them: our SOS First Aid app on the App Store has a BLS section that covers opioid emergencies, laid out in clear numbered steps.

CDC says nearly 80,000 of the 105,007 drug overdose deaths in the United States in 2023, about 76 percent, involved an opioid. CDC also says a potential bystander was present in nearly 43 percent of overdose deaths that year. Naloxone is sold over the counter in all 50 states, so a bystander with naloxone and a plan can make a difference.

Guides

Learn it before you need it

Our SOS First Aid app is the quickest way to start: a pocket study guide for AHA BLS, ACLS, PALS and First Aid CPR/AED built on the 2025 guidelines, with practice quizzes and an AI assistant, for education and reference only (in a life-threatening emergency, call 911). For practice with an instructor, choose Heartsaver First Aid CPR AED ($98), Red Cross BLS ($69) or CPR and Narcan training, or use which CPR class do I need.

Sources

This page is education, not medical or legal advice. In an emergency, call 911 first.